A full time entry level analyst position in bioinformatics for neuroscience projects that involve the study of mouse models of Alzheimer’s disease and postmortem human brain tissues is available starting 6-1-2021.
Projects involve bioinformatic assessment of regional and single population RNA sequencing data derived from mouse models and human postmortem brain tissues.
The research group headed by Dr. Stephen D. Ginsberg at the Center of Dementia Research, Nathan Kline Institute is seeking a highly motivated entry level Bioinformatics Technician to be a part of the laboratory in a collaborative environment.
An ideal candidate would work under direct supervision of senior staff and assist with the bioinformatics components of numerous ongoing projects. Excellent opportunities exist to train to understand and integrate relevant biological concepts into bioinformatic analyses.
Responsibilities include but not limited to:
· Write programs/scripts to query databases including raw files (e.g., FASTQ, BAM files)
· Perform RNA-seq read alignment, normalization, quantification, & read count conversion
· Perform quality control of raw sequencing data using appropriate tools
· Gene based and isoform/transcript quantification
· Data mining and basic statistical assessment
· Preparation of RNA-seq derived data for pathway analysis by KEGG, GO & IPA analysis
· Graphical output of data analysis for publication
· BA/BS in bioinformatics; ideally MS in bioinformatics but not required
· Strong programming skills in R/Bioconductor and Perl with Linux
· Facility with RStudio/Python
· Facility with IPA, KEGG, GO, and Cytoscape
· Proficiency in spreadsheet and database management software
· Facility with RNA-Seq tools (e.g., STAR, TopHat, Salmon/Cufflinks, Trimmomatic)
· Basic knowledge of genomics and transcriptomics
· Basic understanding of brain research
Interested candidates should send a copy of their resume and statement of interest to:
Stephen D. Ginsberg, Ph.D.
Nathan Kline Institute